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Master the MRCP Part 2 with our comprehensive question bank.

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NeurologyeasyQuestion 1Epilepsy

A 55-year-old man has recurrent episodes of impaired awareness preceded by epigastric rising sensation and lip smacking. EEG: temporal spike-wave.

What is first-line medication?
ALamotrigine or levetiracetam
BCarbamazepine
CSodium valproate
DEthosuximide
EPhenytoin
NeurologyhardQuestion 2MND

A 30-year-old woman has progressive hand weakness, fasciculations in upper limbs, and brisk reflexes in lower limbs. Sensation intact.

What is the diagnosis?
AMotor neurone disease (ALS)
BCervical myelopathy
CSyringomyelia
DGuillain-Barré syndrome
EMultifocal motor neuropathy
PharmacologymediumQuestion 3Overdose

A 58-year-old man has tachycardia, dilated pupils, dry mouth, urinary retention, and confusion.

What toxidrome?
AAnticholinergic
BSympathomimetic
CCholinergic
DOpioid
ESerotonin syndrome
Statistics & EBMhardQuestion 4Screening

A screening programme detects cancer earlier but overall mortality is unchanged. Patients appear to survive longer.

What bias explains this?
ALead-time bias
BLength-time bias
CSelection bias
DRecall bias
EPublication bias
NephrologymediumQuestion 5AKI

A 38-year-old man is admitted with dehydration. Creatinine rises from 80 to 210 over 48 hours. Urine output 15 mL/hr.

What AKI stage?
AStage 2
BStage 1
CStage 3
DNot AKI
ECKD
RheumatologymediumQuestion 6GCA

A 25-year-old man has temporal headache, scalp tenderness, jaw claudication. ESR 95. Sudden painless vision loss in left eye.

What causes the vision loss?
AAnterior ischaemic optic neuropathy
BCentral retinal artery occlusion
COptic neuritis
DRetinal detachment
EVitreous haemorrhage
RespiratoryhardQuestion 7Lung Cancer

A 68-year-old woman with small cell lung cancer develops facial swelling, distended neck veins, and dyspnoea worse on bending forward.

What complication is this?
ASVC obstruction
BCardiac tamponade
CPulmonary embolism
DLymphangitis carcinomatosis
EPancoast tumour
HaematologymediumQuestion 8Leukaemia

A 50-year-old woman has WCC 120 with mature granulocytes at all stages and basophilia.

What is the diagnosis?
ACML
BCLL
CAML
DMyelofibrosis
ELeukaemoid reaction
Infectious DiseasesmediumQuestion 9Tropical

A 32-year-old man returns from West Africa with cyclical fevers and rigors. Blood film: ring-form trophozoites. Parasitaemia 5%.

What is the treatment?
AIV artesunate
BOral chloroquine
COral Malarone
DOral quinine + doxycycline
EOral ACT
DermatologyhardQuestion 10Infections

A 35-year-old man has a well-demarcated, erythematous, warm, swollen area on the lower leg with a sharp raised border. Febrile.

What is the diagnosis?
AErysipelas
BCellulitis
CNecrotising fasciitis
DDVT
EContact dermatitis
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